The 49ers will be without star tight end George Kittle for multiple weeks due to a hamstring injury, while Brock Purdy might need to sit out Week 2 after hurting a shoulder and toe in the team’s Week 1 win in Seattle.
Source: ESPN Football News
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49ers' Kittle out weeks; Purdy could miss Week 2
Hour 2: Zach Goodall
September 9, 2025
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